Along the same vein, American culture applauds the "virtues" of extroversion. As Susan Cain explains in her book Quiet, in the early 1900's, led by a man named Dale Carnegie, the agricultural America turned its focus towards being a business powerhouse. At this time, inner attributes that were once valued, such as one's character (like being honorable and well-mannered), soon became sub-par compared to outward characteristics like being fascinating and dynamic. Since then, extroverts have been depicted as more fun, social, funny, interesting, successful, etc. But I'm here to tell you that in reality we're all okay.
“Our culture made a virtue of living only as extroverts. We discouraged the inner journey, the quest for a center. So we lost our center and have to find it again.” Anaïs Nin
Still other studies found "that the right-hemisphere amygdala tends to be larger in extroverts than in introverts, as does the anterior cingulate cortex... Since other studies have implicated the anterior cingulate in social error detection, this may point to some underlying (but still incompletely understood) differences in the ways introverts and extroverts process social missteps." One last intriguing fact that was brought up by Thomas is that "studies have found that cortical neurons of introverts and extroverts may respond differently to the neurotransmitter chemicals gamma-aminobutyric acid (GABA) and N-methyl D-aspartate (NMDA)—an intriguing finding since both GABA and NMDA have both been implicated in anxiety disorders."
In a nutshell, the answer to the question is yes. There are several molecular differences between the introvert's and extrovert's brain.
If any introvert is feeling glum while reading this, thinking that there is no possibility of being "cool" like the idealized extrovert, know that it's not a bad thing to be introverted. In fact, several other countries in the world actually value introversion and quietness over extroversion. And just remember that, even in our extroverted-dominant society, introversion was once the more preferred trait one could hold. In any case, I would like to encourage any introvert feeling at a state of loss to focus on the positive qualities you possess and surround yourself with those who celebrate these positive qualities.
If any introvert is feeling glum while reading this, thinking that there is no possibility of being "cool" like the idealized extrovert, know that it's not a bad thing to be introverted. In fact, several other countries in the world actually value introversion and quietness over extroversion. And just remember that, even in our extroverted-dominant society, introversion was once the more preferred trait one could hold. In any case, I would like to encourage any introvert feeling at a state of loss to focus on the positive qualities you possess and surround yourself with those who celebrate these positive qualities.
“Isn’t it refreshing to know that what comes perfectly natural for you is your greatest strength? Your power is in your nature. You may not think it’s a big deal that you can spend hours immersed in something that interests you—alone—but the extrovert next door has no idea how you do it.” Laurie Helgoe